| Sarissa Capital Management LP | 1,673,395 | $26.7m | 15.0% |
| ACADIAN ASSET MANAGEMENT LLC | 720,984 | $11.5m | 0.0% |
| Kynam Capital Management, LP | 532,982 | $8.5m | 0.5% |
| MORGAN STANLEY | 223,617 | $3.6m | 0.0% |
| Waterfront Wealth Inc. | 213,949 | $3.2m | 0.5% |
| Brooklands Fund Management Ltd | 177,325 | $2.7m | 2.1% |
| Eversept Partners, LP | 145,296 | $2.3m | 0.1% |
| MILLENNIUM MANAGEMENT LLC | 115,808 | $1.8m | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 100,511 | $1.6m | 0.0% |
| CITADEL ADVISORS LLC | 95,364 | $1.5m | 0.0% |
| BNP PARIBAS FINANCIAL MARKETS | 71,813 | $1.1m | 0.0% |
| LCM Capital Management Inc | 51,362 | $818,710 | 0.4% |
| RENAISSANCE TECHNOLOGIES LLC | 48,369 | $771,002 | 0.0% |
| JANE STREET GROUP, LLC | 37,628 | $599,790 | 0.0% |
| George Kaiser Family Foundation | 37,207 | $593,080 | 0.1% |
| SEI INVESTMENTS CO | 29,211 | $465,628 | 0.0% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 29,001 | $462,276 | 0.0% |
| STATE STREET CORP | 25,016 | $398,755 | 0.0% |
| Bleakley Financial Group, LLC | 23,505 | $374,670 | 0.0% |
| AMERIPRISE FINANCIAL INC | 18,982 | $302,573 | 0.0% |
| State of New Jersey Common Pension Fund D | 18,879 | $300,931 | 0.0% |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 18,370 | $292,818 | 0.0% |
| RAYMOND JAMES FINANCIAL INC | 18,165 | $289,550 | 0.0% |
| R Squared Ltd | 16,938 | $269,992 | 0.1% |
| State of Tennessee, Department of Treasury | 15,004 | $239,164 | 0.0% |