| Ikarian Capital, LLC | 503,153 | $3.3m | 0.4% |
| RENAISSANCE TECHNOLOGIES LLC | 478,263 | $3.1m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 379,478 | $2.5m | 0.0% |
| DIMENSIONAL FUND ADVISORS LP | 233,305 | $1.5m | 0.0% |
| BOOTHBAY FUND MANAGEMENT, LLC | 112,544 | $729,285 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 108,413 | $702,616 | 0.0% |
| PERCEPTIVE ADVISORS LLC | 96,982 | $628,443 | 0.0% |
| CITADEL ADVISORS LLC | 73,391 | $475,574 | 0.0% |
| BlackRock, Inc. | 63,547 | $411,785 | 0.0% |
| Bank of New York Mellon Corp | 58,458 | $378,807 | 0.0% |
| JANE STREET GROUP, LLC | 56,741 | $367,682 | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 54,909 | $355,810 | 0.0% |
| STATE STREET CORP | 39,510 | $256,025 | 0.0% |
| UBS Group AG | 26,339 | $170,677 | 0.0% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 26,200 | $169,776 | 0.0% |
| BAILARD, INC. | 24,624 | $159,564 | 0.0% |
| Quadrature Capital Ltd | 24,014 | $155,611 | 0.0% |
| TWO SIGMA INVESTMENTS, LP | 23,981 | $155,397 | 0.0% |
| NORTHERN TRUST CORP | 21,953 | $142,255 | 0.0% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 20,252 | $131,233 | 0.0% |
| Cresset Asset Management, LLC | 19,475 | $126,198 | 0.0% |
| XTX Topco Ltd | 14,118 | $91,485 | 0.0% |
| SIMPLEX TRADING, LLC | 4,544 | $29,445 | 0.0% |
| MORGAN STANLEY | 3,261 | $21,131 | 0.0% |
| Capital Advisors, Ltd. LLC | 437 | $3,000 | 0.0% |