| Jupiter Topco LLC | 9,783,192 | $100.8m | 0.0% |
| Saturn V Capital Management LP | 4,658,429 | $48.0m | 6.9% |
| EVENTIDE ASSET MANAGEMENT, LLC | 3,891,019 | $40.1m | 0.5% |
| STATE STREET CORP | 2,996,935 | $30.9m | 0.0% |
| BlackRock, Inc. | 2,989,972 | $30.8m | 0.0% |
| Deep Track Capital, LP | 2,775,000 | $28.6m | 0.4% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2,507,122 | $25.8m | 0.0% |
| Opaleye Management Inc. | 2,345,000 | $24.2m | 2.2% |
| MILLENNIUM MANAGEMENT LLC | 2,066,426 | $21.3m | 0.0% |
| UBS Group AG | 1,941,817 | $20.0m | 0.0% |
| MARSHALL WACE, LLP | 1,794,908 | $18.5m | 0.0% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,739,919 | $17.9m | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 1,473,409 | $15.2m | 0.0% |
| GREAT POINT PARTNERS LLC | 1,277,642 | $13.2m | 2.5% |
| GEODE CAPITAL MANAGEMENT, LLC | 1,201,097 | $12.4m | 0.0% |
| Velan Capital Investment Management LP | 1,085,000 | $11.2m | 6.8% |
| Bleichroeder LP | 1,000,000 | $10.3m | 1.8% |
| Logos Global Management LP | 1,000,000 | $10.3m | 0.4% |
| FRANKLIN RESOURCES INC | 969,120 | $10.0m | 0.0% |
| Burkehill Global Management, LP | 544,118 | $5.6m | 0.2% |
| AMERIPRISE FINANCIAL INC | 518,881 | $5.3m | 0.0% |
| CITADEL ADVISORS LLC | 506,157 | $5.2m | 0.0% |
| Blue Owl Capital Holdings LP | 437,552 | $4.5m | 0.7% |
| NORTHERN TRUST CORP | 418,051 | $4.3m | 0.0% |
| Balyasny Asset Management L.P. | 417,227 | $4.3m | 0.0% |