| Velan Capital Investment Management LP | 2,668,395 | $1.1m | 0.7% |
| ACORN CAPITAL ADVISORS, LLC | 1,438,159 | $604,027 | 0.2% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,352,106 | $569,237 | 0.1% |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,172,021 | $493,421 | 0.0% |
| Rock Springs Capital Management LP | 1,100,726 | $463,406 | 0.0% |
| Carlyle Group Inc. | 1,066,189 | $448,866 | 0.0% |
| GSA CAPITAL PARTNERS LLP | 534,697 | $225,000 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 486,933 | $204,999 | 0.0% |
| Lion Point Capital, LP | 465,000 | $195,765 | 0.9% |
| GEODE CAPITAL MANAGEMENT, LLC | 263,808 | $111,086 | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 237,900 | $100,156 | 0.0% |
| BlackRock, Inc. | 169,627 | $71,413 | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 149,943 | $63,126 | 0.0% |
| ADAR1 Capital Management, LLC | 140,000 | $58,940 | 0.0% |
| Quarry LP | 131,529 | $55,374 | 0.0% |
| JANE STREET GROUP, LLC | 101,743 | $42,834 | 0.0% |
| UBS Group AG | 58,759 | $24,737 | 0.0% |
| Jain Global LLC | 51,185 | $21,549 | 0.0% |
| OSAIC HOLDINGS, INC. | 45,850 | $19,298 | 0.0% |
| STATE STREET CORP | 44,699 | $18,818 | 0.0% |
| NORTHERN TRUST CORP | 41,882 | $17,632 | 0.0% |
| DIKER MANAGEMENT LLC | 35,000 | $15,000 | 0.0% |
| Qube Research & Technologies Ltd | 33,722 | $14,197 | 0.0% |
| XTX Topco Ltd | 33,406 | $14,064 | 0.0% |
| SIMPLEX TRADING, LLC | 28,591 | $12,036 | 0.0% |