| Essex Woodlands Management, Inc. | 28,195,249 | $108.6m | 42.7% |
| BlackRock, Inc. | 12,154,466 | $46.8m | 0.0% |
| Nantahala Capital Management, LLC | 9,535,104 | $36.7m | 0.6% |
| Trigran Investments, Inc. | 7,173,770 | $27.6m | 5.1% |
| STATE STREET CORP | 5,578,920 | $21.5m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 5,187,053 | $20.0m | 0.0% |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 4,073,100 | $15.7m | 0.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 3,143,488 | $12.1m | 0.0% |
| GOLDMAN SACHS GROUP INC | 2,665,562 | $10.3m | 0.0% |
| AQR CAPITAL MANAGEMENT LLC | 2,467,005 | $9.5m | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 2,444,230 | $9.4m | 0.0% |
| PUNCH & ASSOCIATES INVESTMENT MANAGEMENT, INC. | 2,058,089 | $7.9m | 0.4% |
| DIMENSIONAL FUND ADVISORS LP | 1,944,852 | $7.5m | 0.0% |
| CANNELL CAPITAL LLC | 1,870,436 | $7.2m | 4.8% |
| NORTHERN TRUST CORP | 1,317,575 | $5.1m | 0.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1,290,476 | $5.0m | 0.0% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1,266,571 | $4.9m | 0.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,241,916 | $4.8m | 0.0% |
| Meros Investment Management, LP | 1,121,929 | $4.3m | 1.4% |
| MORGAN STANLEY | 1,043,286 | $4.0m | 0.0% |
| Qube Research & Technologies Ltd | 990,228 | $3.8m | 0.0% |
| CITADEL ADVISORS LLC | 825,838 | $3.2m | 0.0% |
| JANE STREET GROUP, LLC | 792,311 | $3.1m | 0.0% |
| VANGUARD FIDUCIARY TRUST CO | 775,085 | $3.0m | 0.0% |
| KENNEDY CAPITAL MANAGEMENT LLC | 770,075 | $3.0m | 0.1% |