| Voss Capital, LP | 5,261,921 | $5.5m | 0.3% |
| Cable Car Capital, LP | 5,195,000 | $5.4m | 0.1% |
| ADAR1 Capital Management, LLC | 4,500,000 | $4.7m | 0.2% |
| VANGUARD CAPITAL MANAGEMENT LLC | 3,377,910 | $3.5m | 0.0% |
| BIOS Capital Management, LP | 2,982,375 | $3.1m | 7.4% |
| Ikarian Capital, LLC | 2,950,000 | $3.1m | 0.3% |
| GREAT POINT PARTNERS LLC | 2,575,000 | $2.7m | 0.5% |
| CITADEL ADVISORS LLC | 2,438,711 | $2.5m | 0.0% |
| Velan Capital Investment Management LP | 1,700,000 | $1.8m | 1.1% |
| Senvest Management, LLC | 1,230,895 | $1.3m | 0.0% |
| Prosight Management, LP | 1,100,000 | $1.1m | 0.2% |
| Bleichroeder LP | 1,000,000 | $1.0m | 0.2% |
| BOOTHBAY FUND MANAGEMENT, LLC | 889,450 | $925,028 | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 733,139 | $762,540 | 0.0% |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 511,610 | $532,074 | 0.1% |
| VANGUARD FIDUCIARY TRUST CO | 382,515 | $397,816 | 0.0% |
| STATE STREET CORP | 379,604 | $394,788 | 0.0% |
| Empery Asset Management, LP | 370,834 | $385,667 | 0.4% |
| Sigma Planning Corp | 353,677 | $367,824 | 0.0% |
| BlackRock, Inc. | 326,204 | $339,253 | 0.0% |
| Texas Capital Bank Wealth Management Services Inc | 300,758 | $312,789 | 0.0% |
| Sequoia Financial Advisors, LLC | 250,000 | $260,000 | 0.0% |
| GAGNON SECURITIES LLC | 229,070 | $238,233 | 0.0% |
| Stonepine Capital Management, LLC | 218,038 | $226,760 | 0.1% |
| Palogic Value Management, L.P. | 180,000 | $187,200 | 0.1% |