| Jupiter Topco LLC | 11,324,191 | $643.3m | 0.3% |
| BlackRock, Inc. | 8,020,663 | $455.7m | 0.0% |
| FMR LLC | 7,096,614 | $403.2m | 0.0% |
| BANK OF AMERICA CORP /DE/ | 4,568,341 | $259.5m | 0.0% |
| STATE STREET CORP | 4,256,224 | $241.8m | 0.0% |
| VANGUARD CAPITAL MANAGEMENT LLC | 4,108,694 | $233.4m | 0.0% |
| PERCEPTIVE ADVISORS LLC | 3,752,574 | $213.2m | 3.2% |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 2,812,514 | $159.8m | 0.2% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,569,356 | $146.0m | 0.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 2,371,887 | $134.8m | 0.0% |
| Rock Springs Capital Management LP | 2,179,069 | $123.8m | 6.0% |
| Kynam Capital Management, LP | 2,000,000 | $113.6m | 6.3% |
| Stephens Investment Management Group LLC | 1,875,304 | $106.5m | 1.1% |
| RENAISSANCE TECHNOLOGIES LLC | 1,833,079 | $104.1m | 0.1% |
| EMERALD ADVISERS, LLC | 1,600,886 | $90.9m | 2.1% |
| ARMISTICE CAPITAL, LLC | 1,572,539 | $89.3m | 1.1% |
| TWO SIGMA INVESTMENTS, LP | 1,565,656 | $88.9m | 0.1% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1,541,617 | $87.6m | 0.0% |
| GOLDMAN SACHS GROUP INC | 1,535,321 | $87.2m | 0.0% |
| WELLINGTON MANAGEMENT GROUP LLP | 1,533,080 | $87.1m | 0.0% |
| Qube Research & Technologies Ltd | 1,443,230 | $82.0m | 0.1% |
| D. E. Shaw & Co., Inc. | 1,440,469 | $81.8m | 0.0% |
| Driehaus Capital Management LLC | 1,439,134 | $81.8m | 0.5% |
| MARSHALL WACE, LLP | 1,333,207 | $75.7m | 0.1% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,318,616 | $74.9m | 0.0% |