| GordonMD Global Investments LP | 10,024,909 | $30.2m | 14.6% |
| Pfizer Inc | 7,032,770 | $19.5m | 11.4% |
| Laurion Capital Management LP | 4,900,888 | $14.8m | 0.4% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2,075,997 | $6.2m | 0.0% |
| Atle Fund Management AB | 966,459 | $2.9m | 0.8% |
| BlackRock, Inc. | 867,934 | $2.6m | 0.0% |
| Palo Alto Investors LP | 864,277 | $2.6m | 0.4% |
| MARSHALL WACE, LLP | 830,544 | $2.5m | 0.0% |
| RENAISSANCE TECHNOLOGIES LLC | 772,232 | $2.3m | 0.0% |
| GEODE CAPITAL MANAGEMENT, LLC | 591,849 | $1.8m | 0.0% |
| Woodline Partners LP | 523,999 | $1.6m | 0.0% |
| 683 Capital Management, LLC | 459,367 | $1.4m | 0.1% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 428,606 | $1.3m | 0.0% |
| Longaeva Partners L.P. | 353,582 | $1.1m | 0.0% |
| Decheng Capital LLC | 326,810 | $983,698 | 0.1% |
| VANGUARD FIDUCIARY TRUST CO | 302,986 | $911,988 | 0.0% |
| JANE STREET GROUP, LLC | 290,090 | $873,171 | 0.0% |
| STATE STREET CORP | 248,837 | $748,999 | 0.0% |
| MILLENNIUM MANAGEMENT LLC | 233,004 | $701,342 | 0.0% |
| UBS Group AG | 155,217 | $467,203 | 0.0% |
| Bank of New York Mellon Corp | 133,996 | $403,328 | 0.0% |
| ACADIAN ASSET MANAGEMENT LLC | 126,793 | $380,000 | 0.0% |
| NORTHERN TRUST CORP | 123,959 | $373,117 | 0.0% |
| NewEdge Wealth, LLC | 116,006 | $349,178 | 0.0% |
| XTX Topco Ltd | 110,939 | $333,926 | 0.0% |